Yes, you will be able to orient your Pen Tablet and the Quick Keys (purchased in the Bundle or individually) either on the left or the right side of your desk.

For the Pen Tablet: 

The USB port is centered at the top of the Pen Tablet on all models, allowing you to place the Pen Tablet either on the Left-side or the Right-Side of your keyboard for maximum comfort.

Using the Pen Tablet in wireless mode gives you even more freedom to orientate the Pen Tablet how you would like without the USB cable getting in the way. 

For the Quick Keys: 

With the Quick Keys, you can change the orientation to meet your environment or handedness needs easily.

Below is the instruction that will walk you through the process. 

Once you have opened the Setting Program, select [1] My Quick Keys from the Left-navigation menu. 

In the upper right corner below the Gear icon, select [2] Customize, then [3] choose Quick Set Keys Orientation, and lastly [4] select any one of the four orientations in the drop-down menu. 

The orientation of the Quick Key is not able to be assigned by application. It is a global setting.