That is a great question. Yes, the Xencelabs driver for both the macOS and Windows 10 platforms is designed to be over-installed. This helps make the driver update process quicker and easier for you.
Please note: if you have customized your driver, I recommend that you save your Xencelabs Preferences on your computer before installing the new driver.
Here is a link to saving your custom setting: https://xencelabsassist.freshdesk.com/en/support/solutions/articles/67000662593-can-i-save-my-custom-tablet-settings-